Angioimmunoblastic Lymphadenopathy with Dysproteinemia (AILD) is a rare and aggressive type of non-Hodgkin lymphoma.
Characteristics:
1. Enlarged lymph nodes
2. Abnormal immune response
3. Presence of dysproteinemia (abnormal proteins in the blood)
4. Often associated with autoimmune disorders and infections
Symptoms:
1. Fever
2. Weight loss
3. Fatigue
4. Swollen lymph nodes
5. Skin rash
6. Joint pain
7. Respiratory symptoms (e.g., cough, shortness of breath)
Causes:
1. Genetic mutations
2. Abnormal immune response
3. Infections (e.g., Epstein-Barr virus)
4. Autoimmune disorders (e.g., rheumatoid arthritis)
Diagnosis:
1. Biopsy of lymph nodes
2. Blood tests (e.g., complete blood count, protein electrophoresis)
3. Imaging studies (e.g., CT scan, MRI)
4. Flow cytometry and immunohistochemistry
Treatment:
1. Chemotherapy
2. Immunotherapy (e.g., rituximab)
3. Corticosteroids
4. Supportive care (e.g., antibiotics, blood transfusions)
Prognosis:
1. Poor prognosis due to aggressive nature of the disease
2. Median survival time: 1-2 years
3. Response to treatment varies widely among patients.
This article is for information purpose only. Please consult your doctor for the treatment